brain injury
Research Topic
Language: English
This is a research topic created to provide authors with a place to attach new problem publications.
Research problems linked to this topic
- Traumatic brain injury (TBI) is a major cause of disability and death globally.
- After traumatic brain injury, a cascade of metabolic changes promotes the development of secondary brain damage.
- Hypoxic brain injury is the largest contributor to disability and mortality after cardiac arrest.
- Intrapartum hypoxic ischaemic insult remains an important cause of perinatally acquired brain injury in full term neonates.
- Posterior fossa acute extradural hematoma is a rare but potentially fatal disease in children.
- Automobile crashes are one of the leading causes of death in the United States, especially for younger and older drivers.
- Carotid dissection is a major complication of blunt head and neck trauma.
- The blood-brain barrier acts as a major barrier for the entrance of most therapeutics into the brain, impeding treatment for neurological disorders.
- About 20% of Iraq and Afghanistan Veterans have sustained a traumatic brain injury (TBI), which can result in postconcussive symptoms and difficulty transitioning from the military to civilian employment and postsecondary education.
- In neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, multiple sclerosis and amyotrophic lateral sclerosis, neuroinflammation can lead to blood-brain barrier (BBB) breakdown.
- Cerebral small vessel disease (SVD), a common feature of brain aging, is characterized by lacunar infarcts, microbleeds, leukoaraiosis, and a leaky blood-brain barrier.