malaria
Research Topic
Language: English
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- Parasitization by malaria-inducing Plasmodium falciparum leads to structural, biochemical, and mechanical modifications to the host red blood cells (RBCs).
- Malaria is a life threatening disease with a major impact on global health.
- Malaria and typhoid fever are endemic diseases in Cameroon, with overlapping signs and symptoms.
- Malaria is caused by four species of apicomplexan protozoa belonging to the genus Plasmodium.
- The capacity of mosquitoes to resist insecticides threatens the control of diseases such as dengue and malaria.
- Drug and multidrug-resistant Plasmodium falciparum malaria has existed in Thailand for several decades.
- Artemisinin-based combination therapies (ACTs) are currently the first-line drugs for treating uncomplicated falciparum malaria, the most deadly of the human malarias.
- In Sub-Saharan Africa (SSA), where malaria transmission is stable, malaria infection in pregnancy adversely affects pregnant women, fetuses, and newborns and is often asymptomatic.
- Multi-genotype malaria infections are frequent in endemic area, and people commonly harbour several genetically distinct Plasmodium falciparum variants.