biological tissue
Research Topic
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- Periodontal disease is categorized by the destruction of periodontal tissues.
- Regeneration of nerve, which has limited ability to undergo self-healing, is one of the most challenging areas in the field of tissue engineering.
- Visualizing cells in three-dimensional (3D) scaffolds has been one of the major challenges in tissue engineering.
- Dentin regeneration is challenging due to its complicated anatomical structure and the shortage of odontoblasts.
- The limited supply of bone graft is a major problem in human organ transplantation costing lives of many worldwide.
- Mechanical characterization of soft biological tissue is becoming more and more prevalent.
- The complex structure and properties of biological tissues as well as their in situ environment often make it difficult to self-heal.
- Conventional in vitro circulating tumor cell (CTC) detection methods are always limited by blood sample volume because of the requirement of a large amount of blood.
- Fracture healing could be stimulated with osteoinductive bone morphogenetic proteins (bmp's), such as osteogenic protein-1 (OP-1), but little is known about its effectiveness in stimulation of fracture healing.
- Organ printing is a complex and challenging process in execution due to the lack of fundamental understanding of tissue and organ formation, and problems associated with giving the organ-conforming 3D shapes.